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SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Synonimy:
EAAT2, GLT-1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2

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Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Gatunek
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Gatunek
rat, human
(±)-AMPA, solid,
Gatunek
rat
Kainic acid monohydrate, ≥99% (TLC),
Gatunek
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Gatunek
rat, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-Glutamate Transporter Antibody, Glial, serum, Chemicon®,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-Excitatory Amino Acid Transporter (GLT-1) Rabbit pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
rat
Zastosowanie
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Dihydrokainic acid, ≥98% (HPLC), powder,
Gatunek
rat, human
(Aminomethyl)phosphonic acid, 99%,
Gatunek
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Gatunek
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SLC1A2,
Gatunek
human