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PTGIS

prostaglandin I2 (prostacyclin) synthase

Synonimy:
CYP8, CYP8A1, PGIS, PTGI
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5740) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • Mouse(19223) prostaglandin I2 (prostacyclin) synthase
  • Rat(25527) prostaglandin I2 (prostacyclin) synthase
  • cow(282021) prostaglandin I2 (prostacyclin) synthase
  • sheep(101116418) prostaglandin I2 (prostacyclin) synthase
  • Goat(100860894) prostaglandin I2 (prostacyclin) synthase
  • naked mole-rat(101700601) prostaglandin I2 (prostacyclin) synthase
  • domestic guinea pig(100734621) prostaglandin I2 (prostacyclin) synthase
  • Zebrafish(559148) prostaglandin I2 (prostacyclin) synthase
  • Horse(100071412) prostaglandin I2 (prostacyclin) synthase
  • domestic cat(101082050) prostaglandin I2 (prostacyclin) synthase
  • dog(485919) prostaglandin I2 (prostacyclin) synthase

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-PTGIS, (C-terminal) antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, human, mouse, rat
Zastosowanie
western blot
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-PTGIS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-PTGIS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Phenylbutazone, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PTGIS,
Gatunek
human
MISSION® esiRNA, targeting mouse Ptgis,
Gatunek
mouse