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Merck

PRKCD

protein kinase C, delta

Synonimy:
MAY1, PKCD, nPKC-delta
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • dog(494005) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Oleic acid, ≥99% (GC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-phospho-PKC δ (pTyr52) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Protein Kinase Cδ antibody produced in rabbit, whole antiserum,
Reaktywność gatunkowa
rat
Zastosowanie
dot blot
microarray

western blot
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-phospho-PKCD (pTyr64) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Phorbol 12,13-dibutyrate, ≥98% (TLC), powder,
Gatunek
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Gatunek
human
Tamoxifen citrate salt, ≥99%,
Gatunek
human
Oleic acid, ≥99% (GC),
Gatunek
human
UCN-01, ≥97% (HPLC), powder,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
PKC-δ, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
PKCδ Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKCδ. For use in Kinase Assays.,
Gatunek
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Prkcd,
Gatunek
mouse
MISSION® esiRNA, targeting human PRKCD,
Gatunek
human