PRKCA
protein kinase C, alpha
Synonimy:
AAG6, PKC-alpha, PKCA, PRKACA
Gatunek:
Human PRKCA (5578), Mouse Prkca (18750), Rat Prkca (24680), cow PRKCA (282001), sheep PRKCA (101110074), naked mole-rat Prkca (101716044), Domestic Rabbit PRKCA (100037720), domestic guinea pig Prkca (100302324), domestic guinea pig Prkca (100713627), Zebrafish prkca (497384) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(5578) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
- Mouse(18750) protein kinase C, alpha
- Rat(24680) protein kinase C, alpha
- cow(282001) protein kinase C, alpha
- sheep(101110074) protein kinase C, alpha
- naked mole-rat(101716044) protein kinase C, alpha
- Domestic Rabbit(100037720) protein kinase C, alpha
- domestic guinea pig(100302324) protein kinase C, alpha
- domestic guinea pig(100713627) protein kinase C, alpha
- Zebrafish(497384) protein kinase C, alpha
- domestic cat(101086433) protein kinase C, alpha
- Horse(100063318) protein kinase C, alpha
- dog(490904) protein kinase C, alpha
- chicken(417430) protein kinase C, alpha
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Small Molecule - Activator
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Opis
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Small Molecule - Agonist
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Opis
Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PKC Antibody (α, β, γ), clone M110, clone M110, Upstate®, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-phospho-PKC α (pTyr658) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Anti-PKC α antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-PKC alpha-S657/Y658 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-Phospho-PKC alpha-T638 antibody produced in rabbit, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Small Molecule - Inhibitor
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Proteins
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Protein kinase Cα isozyme human, ≥70% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Gatunek
human
PKCα Protein, active, 10 µg, Active, recombinant, full-length human PKCα, containing N-terminal His6 tag. For use in Kinase Assays.,
Gatunek
human
PKC-α, active, GST tagged from Xanopus sp., PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
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