PDE4B
phosphodiesterase 4B, cAMP-specific
Synonimy:
DPDE4, PDE4B5, PDEIVB
Gatunek:
Human PDE4B (5142), Mouse Pde4b (18578), Rat Pde4b (24626), Domestic Rabbit PDE4B (100355058), naked mole-rat Pde4b (101703441), domestic guinea pig Pde4b (100720296), cow PDE4B (100124505), sheep PDE4B (101111757), chicken PDE4B (424700), Horse PDE4B (100053961) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(5142) Summary: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(18578) phosphodiesterase 4B, cAMP specific
- Rat(24626) phosphodiesterase 4B, cAMP specific
- Domestic Rabbit(100355058) phosphodiesterase 4B, cAMP-specific
- naked mole-rat(101703441) phosphodiesterase 4B, cAMP-specific
- domestic guinea pig(100720296) phosphodiesterase 4B, cAMP-specific
- cow(100124505) phosphodiesterase 4B, cAMP-specific
- sheep(101111757) phosphodiesterase 4B, cAMP-specific
- chicken(424700) phosphodiesterase 4B, cAMP-specific
- Horse(100053961) phosphodiesterase 4B, cAMP-specific
- domestic cat(101081316) phosphodiesterase 4B, cAMP-specific
- dog(479540) phosphodiesterase 4B, cAMP-specific
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Numer produktu
Opis
Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PDE4B2 Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-PDE4B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-PDE4B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rat
Zastosowanie
western blot
Anti-PDE4B Antibody, clone 1E9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot