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OGDH

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

Synonimy:
AKGDH, E1k, OGDC
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4967) Summary: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
  • Mouse(18293) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • Rat(360975) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • chicken(426429) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • cow(534599) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • domestic cat(101096048) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • dog(475499) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • domestic guinea pig(100724083) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • naked mole-rat(101716205) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • Domestic Rabbit(100359048) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • sheep(101115360) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-OGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-OGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-OGDH antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, horse, human
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human KIAA0825,
Gatunek
human
MISSION® esiRNA, targeting human OGDH,
Gatunek
human