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Merck

MAPK1

mitogen-activated protein kinase 1

Synonimy:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1

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ELISA

Numer produktu
Opis
Gatunek
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Gatunek
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Gatunek
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Gatunek
rat, human, mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-MAP Kinase1/2 Antibody, clone 12D4, Upstate®, from mouse,
Reaktywność gatunkowa
avian, canine, human, mouse, rat
Zastosowanie
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-MAPK1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Zastosowanie
immunohistochemistry
western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Anti-ERK2/MAPK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
xenopus, bovine, chicken, chimpanzee, human, mouse
Zastosowanie
ELISA
western blot
Anti-ERK1/ERK2 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Adenine, BioReagent, suitable for cell culture,
Gatunek
human, rat, mouse
Adenine, ≥99%,
Gatunek
human, rat, mouse
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MAPK1,
Gatunek
human