Przejdź do zawartości
Merck

GABRB3

gamma-aminobutyric acid (GABA) A receptor, beta 3

Synonimy:
ECA5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2562) Summary: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
  • Mouse(14402) gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
  • Rat(24922) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • Zebrafish(566922) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • cow(529593) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • Horse(100050803) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • domestic cat(100286790) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • chicken(396290) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • dog(606913) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • sheep(101114905) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • naked mole-rat(101711687) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • domestic guinea pig(100731340) gamma-aminobutyric acid (GABA) A receptor, beta 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Gatunek
human
Isoguvacine hydrochloride, solid,
Gatunek
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Gatunek
human
Piperidine-4-sulfonic acid, ,
Gatunek
human
Oxazepam, ,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Gatunek
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Gatunek
human
trans-Dehydroandrosterone, ≥99%,
Gatunek
human, rat
Oxazepam, ,
Gatunek
human
Midazolam maleate salt, ,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Picrotoxin, powder,
Gatunek
human
Pregnenolone sulfate sodium salt, ,
Gatunek
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Gatunek
human
SR-95531, ≥98% (HPLC), powder,
Gatunek
human
trans-Dehydroandrosterone, ≥99%,
Gatunek
human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GABRB3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Anti-GABRB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
Monoclonal Anti-GABRB3 antibody produced in mouse, clone S87-25, 1 mg/mL, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
NO-711 hydrochloride, ≥98% (HPLC),
Gatunek
human
(±)-Vigabatrin, ,
Gatunek
human
2,6-Diisopropylphenol, 97%,
Gatunek
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Etomidate, >98% (HPLC), powder,
Gatunek
human
Flumazenil, >99% (HPLC), solid,
Gatunek
rat, human
Carbamazepine, powder,
Gatunek
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GABRB3,
Gatunek
human