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Merck

EGFR

epidermal growth factor receptor

Synonimy:
ERBB, ERBB1, HER1, PIG61, mENA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(13649) epidermal growth factor receptor
  • Rat(24329) epidermal growth factor receptor
  • fruit fly(37455) Epidermal growth factor receptor
  • cow(407217) epidermal growth factor receptor
  • Horse(100067755) epidermal growth factor receptor
  • domestic cat(100510799) epidermal growth factor receptor
  • dog(404306) epidermal growth factor receptor
  • chicken(396494) epidermal growth factor receptor
  • domestic guinea pig(100725363) epidermal growth factor receptor
  • naked mole-rat(101723771) epidermal growth factor receptor
  • sheep(780479) epidermal growth factor receptor

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ELISA

Numer produktu
Opis
Gatunek
Mouse EGFR ELISA, for serum, plasma and cell culture supernatants,
Gatunek
mouse
Phosphotyrosine EGFR / Epidermal Growth Factor Receptor ELISA Kit, ,
Gatunek
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr1068) in cultured cell lines, 96 assays,
Gatunek
human
Cell-Based ELISA for detecting phospho-EGFR, in cultured cell lines, 96 assays,
Gatunek
human
Phospho-EGFR (pTyr1045) ELISA Kit, for detection of human phospho-egfr (pTyr1045) in cell and tissue lysates,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Tyrphostin AG 1478, ≥98%,
Gatunek
human, mouse
SU 5416, ≥98% (HPLC),
Gatunek
human, mouse
Genistein, synthetic, ≥98% (HPLC), powder,
Gatunek
mouse, human, rat
Genistein, from Glycine max (soybean), ~98% (HPLC),
Gatunek
mouse, human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-EGFR PE produced in mouse, ,
Reaktywność gatunkowa
horse
Zastosowanie
flow cytometry
Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse, clone F4, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anti-Epidermal Growth Factor Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
mouse
Zastosowanie
immunohistochemistry
western blot
Anti-phospho-EGFR (pSer1071) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-EGF Receptor antibody, Mouse monoclonal, clone 225, purified from hybridoma cell culture,
Reaktywność gatunkowa
human
Zastosowanie
immunoprecipitation (IP)

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
DAPH, ≥98% (HPLC), solid,
Gatunek
human
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Erlotinib hydrochloride, ,
Gatunek
human
Gefitinib, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
PKI-166, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Gatunek
human
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Gatunek
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Gatunek
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Gatunek
human
EGFR (D746-750 T790M C797S), Active, PRECISIO® Kinase, recombinant,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human EGFR,
Gatunek
human
MISSION® esiRNA, targeting mouse Egfr,
Gatunek
mouse