EGFR
epidermal growth factor receptor
ERBB, ERBB1, HER1, PIG61, mENA
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...Więcej
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
Custom & Knockdown Gene Products
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Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Cell-Based ELISA for detecting phospho-EGFR (pTyr1068) in cultured cell lines, 96 assays,
human
Phospho-EGFR (pTyr1045) ELISA Kit, for detection of human phospho-egfr (pTyr1045) in cell and tissue lysates,
human
Small Molecule - Antagonist
Antibodies
Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse, clone F4, ascites fluid,
human
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anti-Epidermal Growth Factor Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
mouse
immunohistochemistry
western blot
western blot
Anti-phospho-EGFR (pSer1071) antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
western blot
western blot
Anti-EGF Receptor antibody, Mouse monoclonal, clone 225, purified from hybridoma cell culture,
human
immunoprecipitation (IP)
Small Molecule - Inhibitor
Proteins
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
human
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
human