EGFR
epidermal growth factor receptor
Synonimy:
ERBB, ERBB1, HER1, PIG61, mENA
Gatunek:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
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ELISA
Product Number
Opis
Gatunek
Phospho-EGFR (pTyr1045) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1045) and pan-egfr in cell and tissue lysates,
Gatunek
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr845) in cultured cell lines, 96 assays,
Gatunek
human
Phospho-EGFR (pSer1070) ELISA Kit, for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates,
Gatunek
human
Phospho-EGFR (pTyr1086) ELISA Kit, for detection of human phospho-egfr (pTyr1086) in cell and tissue lysates,
Gatunek
human
Phospho-EGFR (pTyr1086) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1086) and pan-egfr in cell and tissue lysates,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-EGFRvIII, klon DH8.3, clone DH8.3, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-EGFR antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-EGFR antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-phospho-EGFR (pTyr1197) antibody produced in goat, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-EGFR (Ab-1172) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Opis
Gatunek
EGFR (T790M L858R) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Gatunek
human
EGFR (L861Q), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human