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Merck

CTSB

cathepsin B

Synonimy:
APPS, CPSB
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • chicken(396329) cathepsin B
  • dog(486077) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • Horse(100060963) cathepsin B
  • sheep(780470) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • domestic guinea pig(100714169) cathepsin B

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało przeciw katepsynie B, klon 6I5D7, królicze monoklonalne, ,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anty-katepsyna B (Ab-1) mysie mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Reaktywność gatunkowa
bovine, human, porcine
Zastosowanie
Anty-CTSB, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-Cathepsin B antibody, Mouse monoclonal, clone CB59-4B11, purified from hybridoma cell culture,
Reaktywność gatunkowa
human, rat
Zastosowanie
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Opis
Gatunek
Calpain Inhibitor I, ≥97% (TLC), powder,
Gatunek
human
Diethylcyanamide, 99%,
Gatunek
human
MG-132(R), ≥95% (HPLC),
Gatunek
human
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
Gatunek
human

Proteins

Product Number
Opis
Gatunek
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Gatunek
human
Cathepsin B from bovine spleen, lyophilized powder, ≥10 units/mg protein,
Gatunek
cow
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Gatunek
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Gatunek
human
Cathepsin B Active human, recombinant, expressed in FreeStyle 293-F cells, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting human CTSB,
Gatunek
human
MISSION® esiRNA, targeting mouse Ctsb,
Gatunek
mouse

Small Molecule - Substrate

Product Number
Opis
Gatunek
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride, ,
Gatunek
mouse, human, rat