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Merck

ADRB2

adrenoceptor beta 2, surface

Synonimy:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Product Number
Opis
Gatunek
Salbutamol sulfate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Salmeterol xinafoate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orciprenaline for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Siarczan metaproterenolu, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Pirbuterol acetate, VETRANAL®, analytical standard,
Gatunek
human

Small Molecule - Antagonist

Product Number
Opis
Gatunek
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Gatunek
human
Propranolol hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Timolol maleate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Propranolol, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Timolol maleate, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ADRB2, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-β-2 Adrenergic Receptor antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-ADRB2R/ADRB2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-β2-Adrenergic Receptor Antibody, clone 2B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Opis
Gatunek
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Sotalol, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Gatunek
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Gatunek
human
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting human ADRB2,
Gatunek
human
MISSION® esiRNA, targeting mouse Adrb2,
Gatunek
mouse