TP53
tumor protein p53
Synonimy:
BCC7, LFS1, P53, TRP53
Gatunek:
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Zebrafish(30590) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- cow(281542) tumor protein p53
- sheep(443421) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
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ELISA
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
PhosphoDetect Anti-p53 (pSer¹⁵) (Ab-3) Królik pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
Anti-p53 (wild type) Antibody, clone PAb1620, clone Pab1620, from mouse,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
western blot
Anty-p53 (Ab-1) (Pantropic) mysie mAb (PAb421), lyophilized, clone PAb421, Calbiochem®,
Reaktywność gatunkowa
human, monkey, mouse, rabbit, rat
Zastosowanie
Przeciwciało anty-acetylo-p53 (Lys373, Lys382), serum, Upstate®,
Reaktywność gatunkowa
vertebrates
Zastosowanie
western blot
Białko wiążące anty-p53 1 (Ab-1) Królicze pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
human, mouse
Zastosowanie
Cell Lines
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
Proteins
Numer produktu
Opis
Gatunek
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Gatunek
p53 (1-342) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Gatunek
human
p53 (1-81), wild type, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human
esiRNA
Numer produktu
Opis
Gatunek