00922

Difluoroacetic acid

for LC-MS LiChropur^™, ≥97.5% (GC)

• 동의어(들): DFA
• Linear Formula: F₂CHCO₂H
• CAS Number: 381-73-7
• Molecular Weight: 96.03
• Beilstein: 1098588
• MDL number: MFCD00004220
• UNSPSC 코드: 41116004
• NACRES: NB.21

속성

• 분석: ≥97.5% (GC); 97.5-102.5% (T)
• 기술: LC/MS: suitable
• refractive index: n20/D 1.344 (lit.)
• bp: 132-134 °C (lit.)
• mp: −1 °C (lit.)
• density: 1.526 g/mL at 25 °C (lit.)
• 양이온 미량물: Al: ≤5 ppm; Ca: ≤20 ppm; Cu: ≤5 ppm; Fe: ≤2 ppm; K: ≤50 ppm; Mg: ≤5 ppm; Na: ≤50 ppm
• 적합성: passes test for LC-MS
• SMILES string: OC(=O)C(F)F
• InChI: 1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)
• InChI key: PBWZKZYHONABLN-UHFFFAOYSA-N

설명

일반 설명

Compared to trifluoroacetic acid (TFA), difluoroacetic acid (DFA) exhibits an improved sensitivity in mass spectral detection (ESI) as it has a reduced effect on ion suppression in reversed-phase liquid chromatography (RPLC-MS), while keeping its strong chromatographic performance enhancing effects.

Difluoroaceticacid is used in liquid chromatography-mass spectrometry applications. It is a volatile, low molecular-weight organic acid that improves the ionization and resolution of many molecules.

애플리케이션

Difluoroacetic acid can be used as an:

• Acidifier in liquid chromatography (LC) experiments.
• Ion-pairing agent in the HILIC-MS (hydrophilic interaction liquid chromatography-mass spectrometry) analysis of intact pharmaceutical glycoproteins.

추천 제품

Discover LiChropur^™ reagents ideal for HPLC or LC-MS analysis

법적 정보

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H314,H332,H412
• 예방조치 성명서: P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): 172.4 °F - closed cup
• Flash Point (°C): 78 °C - closed cup