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Merck
모든 사진(2)

주요 문서

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Z4900

Sigma-Aldrich

Zopiclone

동의어(들):

4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester, Imovane

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C17H17ClN6O3
CAS Number:
43200-80-2
Molecular Weight:
388.81
EC Number:
256-138-9
MDL number:
MFCD00133931
UNSPSC 코드:
12352200
PubChem Substance ID:
24278148
NACRES:
NA.77

Quality Level

200

약물 제어

USDEA Schedule IV; psychotrope (France); regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

DMSO: 2 mg/mL
H2O: insoluble

주관자

Dainippon Sumitomo

SMILES string

CN1CCN(CC1)C(=O)OC2N(C(=O)c3nccnc23)c4ccc(Cl)cn4

InChI

1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3

InChI key

GBBSUAFBMRNDJC-UHFFFAOYSA-N

유전자 정보

human ... BZRAP1(9256)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Benzodiazepine receptor agonist

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

픽토그램

Health hazardExclamation markEnvironment
GHS08,GHS07,GHS09

신호어

Warning

유해 및 위험 성명서

H302,H336,H361fd,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2 - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
036M4129V
106M4013V
13160510
13160111
073M4038V

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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문서 라이브러리 방문

Monique A J Mets et al.
Sleep, 34(10), 1327-1334 (2011-10-04)
To evaluate the next-morning residual effects of ramelteon (8 mg), zopiclone (7.5 mg), and placebo on driving performance, memory functioning, psychomotor performance, and mood in healthy adult subjects following bedtime dosing and a middle of the night awakening. Single-center, randomized
Milena Araújo Tonon et al.
Analytical and bioanalytical chemistry, 405(1), 267-273 (2012-11-07)
A new high-performance liquid chromatographic method with triple quadrupole mass spectrometry detection was developed and validated for the quantification of zopiclone enantiomers in rat brain samples. Zopiclone enantiomers were resolved on a CHIRALPAK AD column with a mobile phase consisting
Magdy Younes et al.
Journal of applied physiology (Bethesda, Md. : 1985), 112(2), 249-258 (2011-09-17)
It is generally believed that reflex recruitment of pharyngeal dilator muscles is insufficient to open the airway of obstructive apnea (OSA) patients once it is closed and, therefore, that arousal is required. Yet arousal promotes recurrence of obstruction. There is
G Hajak et al.
PharmacoEconomics, 10 Suppl 1, 29-38 (1995-12-09)
Insomnia, especially when chronic, is associated with disturbances in daytime well-being and performance, resulting in a poor quality of life for those affected. Zopiclone has been proven as a drug that favourably balances sleep induction and maintenance as well as
C Fernandez et al.
Clinical pharmacokinetics, 29(6), 431-441 (1995-12-01)
Zopiclone is a cyclopyrrolone hypnotic agent. It possesses a chiral centre and is commercially available as a racemic mixture. Methods involving high performance liquid chromatography (HPLC), gas chromatography, capillary electrophoresis (CE) and high performance thin layer chromatography have been developed
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