추천 제품
Grade
certified reference material
Quality Level
양식
liquid
특징
Snap-N-Spike®/Snap-N-Shoot®
포장
ampule of 1 mL
제조업체/상표
Cerilliant®
농도
1.0 mg/mL in methanol
기술
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
응용 분야
clinical testing
형식
single component solution
배송 상태
wet ice
저장 온도
−20°C
SMILES string
CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCC(O)C5=N1
InChI
1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3
InChI key
PMXMIIMHBWHSKN-UHFFFAOYSA-N
유전자 정보
human ... DRD2(1813) , HTR2A(3356)
일반 설명
A Snap-N-Spike® Reference Solution suitable to use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. Also known as paliperidone, 9-Hydroxyrisperidone is sold under the brand name Invega, an atypical antipsychotic used for acute and maintenance treatment of schizophrenia. The drug is also the primary metabolite of risperidone, marketed as the atypical antipsychotic Risperdal®.
애플리케이션
- 9-HydroxyrisperiDonesolution for in vitro research: Employed in pharmacological studies to investigate dual antipsychotic therapies in treatment-resistant conditions, enhancing the understanding of drug interactions and efficacy (Warnick et al., 2024).
- High-purity 9-HydroxyrisperiDoneliquid for pharmacological studies: Utilized in crystallography research to assess the impact of alkyl chain length on the crystallization behavior of related compounds, providing insights into drug formulation strategies (Chen et al., 2024).
- Buy 9-HydroxyrisperiDonesolution for receptor binding assays: Applied in the development of novel drug delivery systems such as dissolving microneedles, enhancing the administration of long-acting antipsychotic treatments (Londhe and Bhadale, 2023).
- 9-HydroxyrisperiDoneactive metabolite for antipsychotic research: Analyzed in postmortem toxicological assessments to identify metabolites, improving forensic analysis techniques and therapeutic drug monitoring (Yamagishi et al., 2023).
- Analytical standard 9-HydroxyrisperiDonefor biochemistry labs: Investigated in the synthesis of prodrug microcrystals for extended-release formulations, aiding in the design of more effective and patient-friendly antipsychotic medications (Xu et al., 2022).
법적 정보
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Risperdal is a registered trademark of Johnson & Johnson
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
관련 제품
제품 번호
설명
가격
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
표적 기관
Eyes
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point (°F)
49.5 °F - closed cup
Flash Point (°C)
9.7 °C - closed cup
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Drug and therapeutics bulletin, 50(9), 102-105 (2012-09-12)
For over 40 years, antipsychotic drugs have been used as long-term maintenance treatment to control symptoms and reduce relapse rates in patients with schizophrenia. 'First-generation' oral agents such as haloperidol and chlorpromazine are associated with high levels of unwanted neurological
Caroline M Perry
Paediatric drugs, 14(6), 417-427 (2012-10-12)
Paliperidone, the major active metabolite of risperidone, is an atypical antipsychotic agent formulated as an extended-release (ER) tablet suitable for once-daily oral administration. Paliperidone ER is approved for the treatment of adolescents aged 12-17 years with schizophrenia in the US
Pierre S Chue et al.
Expert review of neurotherapeutics, 12(12), 1399-1410 (2012-12-15)
Paliperidone, or 9-hydroxyrisperidone (Invega(®), Janssen, Antwerp, Belgium) is the major active metabolite of the atypical antipsychotic risperidone (Risperdal(®), Janssen). It possesses a similar, though not identical, receptor pharmacology to the parent molecule. There are additional differences in terms of its
Yvette Roke et al.
Journal of child and adolescent psychopharmacology, 22(6), 432-439 (2012-12-14)
The aim of this study was to investigate the long-term treatment effects of risperidone on prolactin levels and prolactin-related side effects in pubertal boys with autism spectrum disorders (ASD) and disruptive behavior disorders (DBD). Physical healthy 10-20-year-old males with ASD
Treating residual insomnia in schizophrenia: examining the options.
C Andrade et al.
Acta psychiatrica Scandinavica, 127(1), 11-11 (2012-12-18)
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