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Merck
모든 사진(1)

주요 문서

Z0167

Sigma-Aldrich

Zearalanone

동의어(들):

2,4-Dihydroxy-6-(10-hydroxy-6-oxoundecyl)benzoic acid μ-lactone

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About This Item

실험식(Hill 표기법):
C18H24O5
CAS Number:
Molecular Weight:
320.38
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

무균

non-sterile

Quality Level

분석

≥98% (TLC)

양식

powder

solubility

methanol: 9.80-10.20 mg/mL, clear, colorless

배송 상태

ambient

저장 온도

−20°C

SMILES string

C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1

InChI key

APJDQUGPCJRQRJ-LBPRGKRZSA-N

유전자 정보

rat ... Ar(24208)

일반 설명

Zearalanone (ZEA) or F-2 toxin, a nonsteroidal estrogenic mycotoxin is produced by various Fusarium species. Fusarium graminearum is considered as the primary producer of zearalanone. It is usually seen in moldy hay, high-moisture corn, corn infected before harvest etc.

애플리케이션

Zearalanone has been used:
  • as mycotoxin to study its effects on the histology of ovaries in pre-pubertal bitches
  • as a mycotoxin to investigate its influence on selected immunological, haematological and biochemical indexes in bitches
  • as a standard to develop calibration curves in order to study its effects on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
  • as a standard to develop calibration curves to study its level of intoxication in women with neoplastic lesions in the reproductive tract

생화학적/생리학적 작용

Zearalanone is believed to cause vulvovaginitis and estrogenic responses in swine.

픽토그램

Health hazardExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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문서 라이브러리 방문

Preliminary results of monitoring research on zearalenone presence in blood of women with neoplastic lesions in reproductive system
Gajecki M, et al.
Polish Journal of Veterinary Sciences, 7(2), 153-156 (2004)
Toxigenic fungi and mycotoxins in the barley-to-beer chain
Brewing Microbiology, 107-139 (2015)
Łukasz Zielonka et al.
Toxins, 12(3) (2020-03-01)
The objective of this study was to determine the effect of long-term (48 days), per os administration of specific zearalenone (ZEN) doses (20 and 40 μg ZEN/kg BW in experimental groups EI and EII, which were equivalent to 200% and
The effect of low doses of zearalenone and its metabolites on progesterone and 17b-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
Gajecka M, et al.
Toxicon, 76, 260-269 (2013)
MYCOTOXINS Classifications
Encyclopedia of food sciences and nutrition, 4080-4089 (2003)

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