추천 제품
![8-benzyl-3-methyl-3,8-diazabicyclo[3.2.1]octane-2,4-dione AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/345/798/0f41aa4b-04dd-4de7-acd0-ec12535ccd20/640/0f41aa4b-04dd-4de7-acd0-ec12535ccd20.png)
양식
powder
Quality Level
저장 온도
2-8°C
SMILES string
[H][C@]12O[C@]3([H])[C@H](O)C[C@@](C)([C@]34CO4)[C@@]1(CO)[C@H](O)C(=O)C(C)=C2
InChI
1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1
InChI key
LINOMUASTDIRTM-QGRHZQQGSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Deoxynivalenol (DON) is a natural mycotoxin found in Fusarium graminearum and Fusarium culmorum. It belongs to the B-trichothecenes family of mycotoxins.
애플리케이션
Deoxynivalenol has been used:
- as a mycotoxin to induce cytotoxicity in porcine jejunal epithelial cells and study the protective effects of Saccharomyces cerevisiae on the cell viability of host cells.
- to induce toxicity in nude mice to study the effect of probiotics (Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus (LA)) supplementation on host protection
- as a thyroid hormone receptor (TRβ) antagonist in cell-based luciferase reporter gene (CALUX) assay
생화학적/생리학적 작용
Deoxynivalenol (DON) blocks the synthesis of DNA and RNA by inhibiting the process of translation.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Oral
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
이미 열람한 고객
Yang Liu et al.
AMB Express, 9(1), 137-137 (2019-09-05)
Deoxynivalenol (DON) is one of the mycotoxins most frequently encountering in cereal-based foods throughout the world. Saccharomyces cerevisiae was used to alleviate porcine jejunal epithelia cell (IPEC-J2) injury induced by DON in this study. The results indicated that cell viability
Toxicology of deoxynivalenol (vomitoxin).
Rotter B A.
Int J Toxicol Pharmacol Res, 48(1), 1-34 (1996)
Isabel Parraga-Aguado et al.
Journal of environmental management, 158, 74-84 (2015-05-13)
Phytomanagement in terms of phytostabilisation has been proposed as a suitable technique to decrease the environmental risks of metal(loid) enriched mine tailings. Nevertheless, at these sites some issues must be solved to assure the long-term establishment of vegetation (e.g. salinity
Miaomiao Wu et al.
PloS one, 9(7), e100591-e100591 (2014-07-02)
The mycotoxin deoxynivalenol (DON), one of the most common food contaminants, primarily targets the gastrointestinal tract to affect animal and human health. This study was conducted to examine the protective function of glutamic acid on intestinal injury and oxidative stress
Michihiro Ito et al.
Applied and environmental microbiology, 79(5), 1619-1628 (2013-01-01)
Deoxynivalenol (DON) is a natural toxin of fungi that cause Fusarium head blight disease of wheat and other small-grain cereals. DON accumulates in infected grains and promotes the spread of the infection on wheat, posing serious problems to grain production.
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