X2502

Xanthine sodium salt

≥99%

• 동의어(들): 2,6-Dihydroxypurine
• 실험식(Hill 표기법): C₅H₃N₄NaO₂
• CAS Number: 1196-43-6
• Molecular Weight: 174.09
• MDL number: MFCD00069699
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24902137
• NACRES: NA.51

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥99%
• 형태: powder
• 불순물: ≤4% total solvent
• solubility: dilute NaOH: soluble, clear to slightly hazy
• SMILES string: [Na].O=C1NC(=O)c2[nH]cnc2N1
• InChI: 1S/C5H4N4O2.Na.H/c10-4-2-3(7-1-6-2)8-5(11)9-4;;/h1H,(H3,6,7,8,9,10,11);;
• InChI key: JAZQMXVZANZJSO-UHFFFAOYSA-N

설명

일반 설명

Xanthine is an intermediate of purine nucleotide metabolism. It is found in most body tissues and fluids. Xanthine derivatives are present in coffee, tea, and chocolate.

애플리케이션

Xanthine sodium salt has been used as a component of substrate solution for xanthine oxidase during superoxide dismutase (SOD) assay. It has also been used as a supplement in a special-conditioned medium to culture Swiss 3T3 fibroblasts stably transfected with tetracycline (tet)-controlled transactivator and transactivator-controlled tissue transglutaminase cDNA [39] constructs (clone TG3).

생화학적/생리학적 작용

Xanthine acts as a substrate for xanthine oxidase. It elevates cellular cyclic AMP levels by preventing its breakdown and metabolism by inhibition of tissue phosphodiesterases. Xanthine also exhibits anti-inflammatory properties either by the release of anti-inflammatory cytokines or gene transcription regulation or histone deacetylase activation. All these properties of xanthine aid in the relaxation of smooth muscles of the bronchial tree.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H371
• 예방조치 성명서: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves