SML2716
Pitolisant hydrochloride
≥98% (HPLC)
동의어(들):
1-[3-[3-(4-Chlorophenyl)propoxy]propyl]piperidine hudrochloride, 1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine hydrochloride, 3-(4-Chlorophenyl)propyl 3-piperidinopropyl ether hydrochloride, BF 2649, BF2.649, Ciproxidine, Tiprolisant
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C17H26ClNO · HCl
CAS Number:
Molecular Weight:
332.31
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to beige
solubility
H2O: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
Clc1ccc(cc1)CCCOCCCN2CCCCC2.Cl
InChI
1S/C17H26ClNO.ClH/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19;/h7-10H,1-6,11-15H2;1H
InChI key
XLFKECRRMPOAQS-UHFFFAOYSA-N
생화학적/생리학적 작용
Potent and selective competitive antagonist/inverse agonist of histamine H3 receptor
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Repr. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Benjamin Huyts et al.
European journal of pharmacology, 851, 63-68 (2019-02-17)
Pitolisant, a selective inverse agonist for the histamine H3 receptor, is a new treatment for adults suffering from narcolepsy. Numerous studies have shown that striatal H3 receptors can modulate the activity of the dopamine mesolimbic system, a neuronal pathway that
Jorge D Brioni et al.
The Journal of pharmacology and experimental therapeutics, 336(1), 38-46 (2010-09-25)
H(3) antagonists increase the release of brain histamine, acetylcholine, noradrenaline, and dopamine, neurotransmitters that are known to modulate cognitive processes. The ability to release brain histamine supports the effect on attention and vigilance, but histamine also modulates other cognitive domains
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