10171832001

Aldehyde Dehydrogenase

from yeast

• 동의어(들): Aldehyde dehydrogenase
• 효소 위원회 번호: 1.2.1.5 (BRENDA, IUBMB)
• UNSPSC 코드: 12352204

속성

• 생물학적 소스: yeast
• Quality Level: 100
• 양식: lyophilized
• 특이 활성도: ~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
• 포장: pkg of 250 U
• 제조업체/상표: Roche
• 최적 pH: 8.75
• 관련 질환(들): cancer
• 저장 온도: 2-8°C

설명

일반 설명

Aldehyde dehydrogenase (ALDH) is a soluble enzyme and its activity depends on potassium ions and cysteine. The family of ALDH comprises of 19 genes in human. ALDH gene is expressed in the nucleus, cytosol, mitochondria and endoplasmic reticulum of the cell. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems.

애플리케이션

Aldehyde Dehydrogenase has been used to evaluate fiber-optic biosensors for measurement of acetaldehyde (AcH) in liquid phase (AcH biosensor).

생화학적/생리학적 작용

Aldehyde dehydrogenase (ALDH) regulates the non-P450 aldehyde reduction enzyme system. It protects the cell from the effects of toxic aldehydes. Mutations in this gene are associated with Sjogren Larsson syndrome, Larsson syndrome, type II hyperprolinemia and cancer. ALDH takes part in the oxidation of aldehydes to acids. ALDH-2 lowers cardiac ischemia, which arises due to myocardial infarction or post cardiac surgery.

품질

Contaminants: <0.01% “NADH oxidase”, ADH, and LDH each

물리적 형태

Enzyme is stabilized with potassium phosphate buffer, pH approximately 6.

기타 정보

For life science research only. Not for use in diagnostic procedures.

안전성 정보

• 픽토그램: GHS07,GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H332,H373
• 예방조치 성명서: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - STOT RE 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash