SML2532

Jedi2

≥98% (HPLC)

• 동의어(들): 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
• 실험식(Hill 표기법): C₁₀H₈O₃S
• CAS Number: 651005-90-2
• Molecular Weight: 208.23
• MDL number: MFCD01569561
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: [s]1c(ccc1)c2[o]c(c(c2)C(=O)O)C
• InChI: 1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
• InChI key: YXDCRSXNEOKXDE-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Jedi2 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.

Piezo1 channel activator

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H317,H319
• 예방조치 성명서: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable