SML2473

Pitavastatin calcium

≥98% (HPLC)

• 동의어(들): (+)monocalcium bis{(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5dihydroxy-6-heptenoate}, (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt
• 실험식(Hill 표기법): C₂₅H₂₃FNO₄ · 0.5Ca
• CAS Number: 147526-32-7
• Molecular Weight: 440.49
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: powder
• 광학 활성: [α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1)
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• InChI: 1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
• InChI key: RHGYHLPFVJEAOC-FFNUKLMVSA-L

설명

생화학적/생리학적 작용

Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipidemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H361f
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable