SML1624

JNJ-63533054

≥98% (HPLC)

• 동의어(들): (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)benzamide
• 실험식(Hill 표기법): C₁₇H₁₇ClN₂O₂
• CAS Number: 1802326-66-4
• Molecular Weight: 316.78
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D -89 to -99°, c = 1 in ethanol
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: Clc1cc(ccc1)C(=O)NCC(=O)N[C@@H](C)c2ccccc2
• InChI key: MWDVCHRYCKXEBY-LBPRGKRZSA-N

설명

생화학적/생리학적 작용

JNJ-63533054 is a potent and selective agonist of the orphan receptor hGPR139, a GPCR receptor expressed in the brain in circumventricular regions of the habenula and septum. JNJ-63533054 has an EC50 value of 16 nM, crosses the blood-brain barrier, and is orally available.

Potent and selective agonist of hGPR139 with an EC50 value of 16 nM

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319
• 예방조치 성명서: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable