300764

1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole

98%

• 동의어(들): Noreleagnine, THBC, Tetrahydronorharman, Tryptoline
• 실험식(Hill 표기법): C₁₁H₁₂N₂
• CAS Number: 16502-01-5
• Molecular Weight: 172.23
• MDL number: MFCD00004954
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24857939
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 98%
• 양식: liquid
• mp: 206-208 °C (lit.)
• SMILES string: C1Cc2c(CN1)[nH]c3ccccc23
• InChI: 1S/C11H12N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-4,12-13H,5-7H2
• InChI key: CFTOTSJVQRFXOF-UHFFFAOYSA-N
• 유전자 정보: rat ... Htr2a(29595) , Htr2c(25187)

설명

일반 설명

Ozonolysis of the enamine bond of 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole derivatives was studied.

애플리케이션

1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole was employed in alkaloid synthesis and in studies on neurodegenerative diseases.

• Reactant for synthesis of the indolyl-β-carboline alkaloid eudistomin U via IBX mediated room temperature oxidative aromatization
• Reactant for preparation of neuroprotective HDAC6 inhibitors
• Reactant for preparation of aminofuranopyrimidines as EGFR and Aurora A kinase inhibitors
• Reactant for preparation of inhibitors of CDK4
• Reactant for preparation of tetrahydrocarboline derivatives of as human 5-HT5A receptor ligands
• Reactant for preparation of 5-(diaminomethyl)-2,4-aminopyrimidines as dihydrofolate reductase inhibitors and antibacterial agents

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves