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Merck
모든 사진(1)

주요 문서

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SML0647

Sigma-Aldrich

Phenazepam

≥97% (HPLC)

동의어(들):

7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-Bromo-5-(2-chlorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one, BD 98, Fenazepam

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C15H10BrClN2O
CAS Number:
51753-57-2
Molecular Weight:
349.61
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

100

분석

≥97% (HPLC)

양식

powder

색상

white to beige

solubility

DMSO: 20 mg/mL, clear

저장 온도

−20°C

SMILES string

Brc1cc2c(cc1)NC(=O)CN=C2c3c(cccc3)Cl

InChI

1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

InChI key

CGMJQQJSWIRRRL-UHFFFAOYSA-N

생화학적/생리학적 작용

Phenazepam is an agonist of the γ-Aminobutyric acid A (GABAA)-benzodiazepine receptor chloride channel complex.
Phenazepam is the benzodiazepine that exhibit anticonvulsive, anxiolytic, sedative and hypnotic effects in humans and experimental animals. Phenazepam is an agonist of the γ-Aminobutyric acid A (GABAA)-benzodiazepine receptor chloride channel complex.

특징 및 장점

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Danger

유해 및 위험 성명서

H319,H340,H360,H362

Hazard Classifications

Eye Irrit. 2 - Lact. - Muta. 1B - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number
053M4710V

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문서 라이브러리 방문

[Evaluation of the effect of phenazepam and seduxen on the functional state of the cardiovascular system in the acute phase of an infarct].
G Lukhanana
Vrachebnoe delo, (10)(10), 15-18 (1983-10-01)
N Ia Golovenko et al.
Farmakologiia i toksikologiia, 43(2), 144-148 (1980-03-01)
The distribution pattern of 14C-phenazepam and some of its metabolites in the liver, brain and blood plasma at a prolonged (45 days) administration to rats does not differ from that after a single administration. The liver and brain demonstrated an
Peter D Maskell et al.
Journal of forensic and legal medicine, 19(3), 122-125 (2012-03-07)
In the past few years there has been concern in Western Europe and in the US about the rise in abuse of phenazepam, a benzodiazepine that was originally developed in the USSR in the mid- to late 1970s.(1-4) Although phenazepam
Jon B Stephenson et al.
Journal of analytical toxicology, 37(1), 25-29 (2012-10-18)
Phenazepam use in the state of Georgia has increasingly become a trend for a drug market looking at new and different recreational drugs. This paper examines the psychomotor effects of phenazepam on individuals and their ability to operate a motor
John Martin Corkery et al.
Human psychopharmacology, 27(3), 254-261 (2012-03-13)
Phenazepam (fenazepam; 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; PNZ, 'Bonsai') is a benzodiazepine developed in the former Soviet Union during the 1970s to treat neurological disorders, epilepsy, and alcohol withdrawal syndrome. Its recreational use appears to have increased over recent years. Because of the lack

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GABAA Receptors

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