SML0128
M30 dihydrochloride
≥98% (HPLC)
동의어(들):
5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride, M-30 dihydrochloride, VAR10300 dihydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C14H14N2O · 2HCl
CAS Number:
Molecular Weight:
299.20
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
저장 조건
desiccated
색상
green-yellow
solubility
DMSO, heptane and xylene: ≥21 mg/mL
저장 온도
2-8°C
SMILES string
Cl.Cl.CN(CC#C)Cc1ccc(O)c2ncccc12
InChI
1S/C14H14N2O.2ClH/c1-3-9-16(2)10-11-6-7-13(17)14-12(11)5-4-8-15-14;;/h1,4-8,17H,9-10H2,2H3;2*1H
InChI key
XJNICPXVRPOSSO-UHFFFAOYSA-N
애플리케이션
M30 dihydrochloride may be used in monamine oxidase-mediated cell signaling studies.
생화학적/생리학적 작용
M30 is a site-activated iron chelator and monoamine oxidase (MAO) inhibitor; with neuroprotective and anti-apoptotic activity. It is a multifunctional non-toxic, brain permeable iron chelator possessing a neuroprotective propargylamine moiety and an antioxidant-iron chelator moiety. M30 is a selective irreversible inhibitor of mitochondrial brain monoamine oxidases A and B (MAO-A and -B), providing for improved levels of neurotransmitters. It reduces oxidative damage and shows neuroprotective and neurorestorative effects in various neurodegenerative models of ALS, Alzheimer′s and Parkinson′s diseases, and is being investigated in other diseases where oxidative stress is a problem.
특징 및 장점
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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문서
Our company offers many products related to histamine synthesis and metabolism for your research needs.
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