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Merck
모든 사진(2)

문서

SMB00806

Sigma-Aldrich

7-Ketodeoxycholic acid

≥95% (HPLC)

동의어(들):

3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid, 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid

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About This Item

실험식(Hill 표기법):
C24H38O5
CAS Number:
Molecular Weight:
406.56
UNSPSC 코드:
41141802
NACRES:
NA.28

분석

≥95% (HPLC)

형태

powder

포장

pkg of 1 g
pkg of 50 mg

색상

off-white to beige

mp

193—198 °C

작용기

carboxylic acid
ketone

배송 상태

wet ice

저장 온도

−20°C

InChI

1S/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,20,22,25,27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,20+,22+,23+,24-/m1/s1

InChI key

RHCPKKNRWFXMAT-RRWYKFPJSA-N

일반 설명

7-Ketodeoxycholic acid, categorized as a oxo-5beta-cholanic acid, is a bile acid derivative and a metabolite resulting from the degradation of the primary bile acid, cholic acid, by intestinal bacteria. Bile acids, natural steroid amphipathic compounds formed through cholesterol oxidation in the liver, play a crucial role in regulating lipid metabolism. They facilitate the digestion, absorption, and transport of lipids, lipid-soluble vitamins, and related molecules in the gastrointestinal tract. These bile acids also impact various aspects of cholesterol, glucose, and energy balance. However, in specific liver conditions such as intrahepatic cholestasis characterized by reduced bile flow, the accumulation of bile acids at elevated concentrations can lead to severe toxic effects. This makes 7-Ketodeoxycholic acid a compound of interest for biochemical and metabolomics research.

애플리케이션

7-Ketodeoxycholic acid finds application in metabolomics, biochemical and microbiome research.

특징 및 장점

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

기타 정보

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Takaaki Goto et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 846(1-2), 69-77 (2006-09-05)
We developed a highly sensitive and quantitative method to detect bile acid 3-sulfates in human urine employing liquid chromatography/electrospray ionization-tandem mass spectrometry. This method allows simultaneous analysis of bile acid 3-sulfates, including nonamidated, glycine-, and taurine-conjugated bile acids, cholic acid

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