추천 제품
Grade
analytical standard
Quality Level
분석
≥97.0% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
131-135 °C (lit.)
응용 분야
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
형식
neat
저장 온도
2-8°C
SMILES string
O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
InChI
1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChI key
MXXWOMGUGJBKIW-YPCIICBESA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Piperine is a naturally occurring bioactive alkaloid in pepper, which imparts pungency and bitter flavor to it. It has demonstrated health benefits and exhibits therapeutic properties, which include its role as an antimicrobial, antioxidant, antifungal, immunomodulatory and hepatoprotective agent. The inhibition of drug-metabolizing enzymes in hepatic and pulmonary tissues, and the enhancement of drug bioavailability by this compound are reported. It is also found to play an important role in reducing blood glucose, cholesterol and triglycerides.
Piperine is an amide isolated from the plant, Piper longum. It is a known inhibitor of hepatic and intestinal glucuronidation. Piperine is found to exhibit pharmacological properties like antitumor, antipyretic and anti-inflammatory activities.
애플리케이션
Piperine may be used as an analytical reference standard for the quantification of the analyte in:
- Human plasma using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).
- Piper nigrum extract using reversed phase high pressure liquid chromatographic method with UV detection (RP-HPLC-UV).
- Food products using high-performance liquid chromatography with diode array detection (HPLC-DAD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
A liquid chromatography method for the simultaneous determination of curcumin and piperine in food products using diode array detection
Asian Journal of Research in Chemistry, 2(2), 115-118 (2009)
Immunomodulatory and antitumor activity of Piper longum Linn. and piperine
Journal of Ethnopharmacology, 90(2), 339-346 (2004)
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
Planta Medica, 64(04), 353-356 (1998)
Validated HPLC?MS/MS method for simultaneous determination of curcumin and piperine in human plasma
Tropical Journal of Pharmaceutical Research, 11(4), 621-629 (2012)
Preliminary study on inhibition of genotoxicity by piperine in mice
Fitoterapia, 76(3-4), 296-300 (2005)
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