추천 제품
생물학적 소스
alpaca
재조합
expressed in HEK 293 cells (Human cell line)
결합
unconjugated
항체 형태
affinity purified immunoglobulin
항체 생산 유형
secondary antibodies
클론
recombinant monoclonal
형태
lyophilized solid
분자량
100 kDa
종 반응성
Alpaca, mouse
기술
ELISA: 1:5000-1:20000
western blot: 1:5000-1:20000
크기
0.1 mL
색상
colorless
동형
VHH
배송 상태
wet ice
저장 온도
2-8°C
일반 설명
Goat Anti-Mouse IgM(µ chain) Alpaca Heavy chain only Antibody is designed to specifically detect mouse IgM. It is a monovalent, single domain, recombinant antibody fused to goat IgG Fc. Based on immunoelectrophoresis and/or ELISA, Goat Anti-Mouse IgM(µ chain) Alpaca Heavy chain only Antibody reacts with the µ chain of mouse IgM selectively but not with mouse, rabbit, human, cynomolgus, rat, goat IgG.
Most monoclonal antibodies are generated in mouse. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mouse. Each isotype has a different heavy chain. IgM accounts for 5-10% of the immunoglobulin pool and is the predominant antibody in the primary immune response. Unlike IgG, IgM does not contain a hinge region but does contain an additional constant domain. The monomeric form IgM has a molecular weight of 180 KD. It is classically represented as a pentamer of the basic four chain structure held together by a J chain but can also exist in a hexameric form without the J chain and as a monomer on the surface of B-cells.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
Most monoclonal antibodies are generated in mouse. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mouse. Each isotype has a different heavy chain. IgM accounts for 5-10% of the immunoglobulin pool and is the predominant antibody in the primary immune response. Unlike IgG, IgM does not contain a hinge region but does contain an additional constant domain. The monomeric form IgM has a molecular weight of 180 KD. It is classically represented as a pentamer of the basic four chain structure held together by a J chain but can also exist in a hexameric form without the J chain and as a monomer on the surface of B-cells.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
특이성
Fc region of mouse IgM (µ chain specific)
Isotype: VHH domain of alpaca IgG2b/2c fused to goat IgG Fc
Isotype: VHH domain of alpaca IgG2b/2c fused to goat IgG Fc
면역원
Recombinant Alpaca single variable domain secondary nano antibody
포장
100 μg in Glass bottle
물리적 형태
Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose
재구성
Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL
저장 및 안정성
After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Stable for 12 months at -20°C
기타 정보
No cross-reactivity with mouse, rabbit, human, cynomolgus, rat, goat IgG
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신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Aquatic Chronic 3 - Skin Sens. 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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