S2501

Spermidine trihydrochloride

≥98% (TLC)

• 동의어(들): N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
• Linear Formula: NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl
• CAS Number: 334-50-9
• Molecular Weight: 254.63
• Beilstein: 3552356
• EC Number: 206-379-0
• MDL number: MFCD00012918
• UNSPSC 코드: 12352204
• PubChem Substance ID: 24277993
• NACRES: NA.32

속성

• 생물학적 소스: microbial; synthetic
• 분석: ≥98% (TLC)
• 양식: powder
• mp: 257-259 °C (lit.)
• solubility: water: 100 mg/mL, clear, colorless
• 저장 온도: room temp
• SMILES string: Cl[H].Cl[H].Cl[H].NCCCCNCCCN
• InChI: 1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
• InChI key: LCNBIHVSOPXFMR-UHFFFAOYSA-N
• 유전자 정보: human ... NOS1(4842)

설명

일반 설명

The nitric oxide synthase (nNOS) gene is localized on human chromosome 12q24.22. The enzyme is involved in the production of nitric oxide.

애플리케이션

Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.

생화학적/생리학적 작용

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

주의사항

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves