85580

Spermidine trihydrochloride

≥99.0% (AT)

• 동의어(들): N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
• Linear Formula: NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl
• CAS Number: 334-50-9
• Molecular Weight: 254.63
• Beilstein: 3552356
• EC Number: 206-379-0
• MDL number: MFCD00012918
• UNSPSC 코드: 12352204
• PubChem Substance ID: 329769390
• NACRES: NA.77

속성

• 생물학적 소스: microbial; synthetic
• 분석: ≥99.0% (AT)
• 양식: powder
• mp: ~250 °C (dec.); 257-259 °C (lit.)
• solubility: H₂O: 0.1 g/mL, clear, colorless
• 저장 온도: room temp
• SMILES string: Cl[H].Cl[H].Cl[H].NCCCCNCCCN
• InChI: 1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
• InChI key: LCNBIHVSOPXFMR-UHFFFAOYSA-N

설명

일반 설명

Spermidine is a polyamine and a trivalent organic cation.

애플리케이션

Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.

생화학적/생리학적 작용

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.

주의사항

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves