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Merck
모든 사진(1)

주요 문서

S1172

Sigma-Aldrich

Anti-Syntaxin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

동의어(들):

Anti-GEFSP9, Anti-STX1B1, Anti-STX1B2

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

IgG fraction of antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

양식

lyophilized powder

종 반응성

mouse, rat

기술

immunohistochemistry: suitable using rat brain sections
western blot (chemiluminescent): 1:1,000 using rat brain membranes

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

일반 설명

Syntaxin 1 is a membrane protein. It is also known as HPC-1. Neurons express syntaxin 1A.

면역원

highly purified GST fusion protein with the residues 1-265 of rat syntaxin 1A (intracellular, N-terminal).

애플리케이션

Anti-Syntaxin 1 antibody has been used in western blotting and immunohistochemistry.

생화학적/생리학적 작용

Syntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the INL (inner nuclear layer) and OPL(outer plexiform layer). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury.

물리적 형태

After reconstitution, the antibody solution is phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

A Critical role for Bim in retinal ganglion cell death
McKernan DP and Cotter TG
Journal of Neurochemistry, 102(3), 922-930 (2007)
Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
KM Khan, et al.
Iranian Journal of Pharmaceutical Research : IJPR, 3, 10-10 (2004)
Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons
Latina V, et al.
Frontiers in Cellular Neuroscience, 11 (2017)
Chronic exercise enhances insulin secretion ability of pancreatic islets without change in insulin content in non-diabetic rats
Tsuchiya M, et al.
Biochemical and Biophysical Research Communications, 430(2), 676-682 (2013)
SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: a comparative analysis
Schubert V, et al.
Glia, 59(10), 1472-1488 (2011)

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