PZ0015

Trovafloxacin mesylate

>98% (HPLC), powder, Pannexin 1 inhibitor

• 동의어(들): (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate
• 실험식(Hill 표기법): C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H
• CAS Number: 147059-75-4
• Molecular Weight: 512.46
• MDL number: MFCD00913361
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329823684
• NACRES: NA.77

속성

• product name: Trovafloxacin mesylate, >98% (HPLC)
• Quality Level: 100
• 분석: >98% (HPLC)
• 형태: powder
• 색상: white to off-white
• solubility: DMSO: >10 mg/mL
• 저장 온도: room temp
• SMILES string: CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F
• InChI: 1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;
• InChI key: DYNZICQDCVYXFW-AHZSKCOESA-N

설명

애플리케이션

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.

생화학적/생리학적 작용

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.

Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

안전성 정보

• 픽토그램: GHS08,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314,H361
• 예방조치 성명서: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Repr. 2 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable