SML1420

FSL-1

≥80% (HPLC)

• 동의어(들): (R,S)-Pam2Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH, Fibroblast-stimulating Lipopeptide, Pam2CGDPKHPKSF, S-[2,3-Bis[(1-Oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-a-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine
• 실험식(Hill 표기법): C₈₄H₁₄₀N₁₄O₁₈S
• CAS Number: 322455-70-9
• Molecular Weight: 1666.16
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥80% (HPLC)
• 형태: powder
• 색상: white to off-white
• solubility: H₂O: soluble
• 저장 온도: −20°C

설명

생화학적/생리학적 작용

FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-κB in TLR2/TLR6 transfected HEK293 cells.

FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.

재구성

Reconstitute in endotoxin-free water.

기타 정보

Air sensitive

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable