P7556

Progesterone-Water Soluble

powder, BioReagent, suitable for cell culture

• 동의어(들): Progesterone: HBC complex, Progesterone: methyl-β-cyclodextrin complex
• MDL number: MFCD00003658
• UNSPSC 코드: 12352209
• PubChem Substance ID: 57654558
• NACRES: NA.77

속성

• 생물학적 소스: synthetic (organic)
• 제품 라인: BioReagent
• 분석: ≥65% (HPLC)
• 양식: powder
• 농도: ≥65% (HPLC)
• 기술: cell culture | mammalian: suitable
• solubility: H₂O: 25 mg/mL, clear to slightly hazy
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• InChI key: RJKFOVLPORLFTN-LEKSSAKUSA-N
• 유전자 정보: human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

설명

일반 설명

Progesterone is a steroid hormone secreted by the ovaries.

애플리케이션

Progesterone-Water Soluble has been used:

• for in vitro maturation of oocyte complexes
• as a σ1R antagonist to study its effect on sigma 1 receptor
• to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

생화학적/생리학적 작용

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

포장

Package size based on progesterone content

기타 정보

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H351,H360FD,H362
• 예방조치 성명서: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Hazard Classifications: Carc. 2 - Lact. - Repr. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable