P3075

Phenylarsine oxide

≥97%, powder

• 동의어(들): Arzene, Oxophenylarsine, PAO
• 실험식(Hill 표기법): C₆H₅AsO
• CAS Number: 637-03-6
• Molecular Weight: 168.02
• Beilstein: 2935227
• EC Number: 211-275-3
• MDL number: MFCD00001990
• UNSPSC 코드: 12352119
• PubChem Substance ID: 24898387
• NACRES: NA.77

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 100
• 분석: ≥97%
• 양식: powder
• 색상: white to off-white
• mp: 145-148 °C
• solubility: DMSO: 50 mg/mL
• SMILES string: O=[As]c1ccccc1
• InChI: 1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H
• InChI key: BQVCCPGCDUSGOE-UHFFFAOYSA-N

설명

일반 설명

Phenylarsine oxide (PhAsO⁴) is a bifunctional SH group chemical. It is hydrophobic in nature.

애플리케이션

Phenylarsine oxide has been used to infuse animals with a nigrostriatal transection, to determine whether peroxovanadium (pVa) would synergize with brain-derived neurotrophic factor (BDNF).

생화학적/생리학적 작용

Phenylarsine oxide (PAO) can reduce the motility and sustainability of Setaria cervi. It has the ability to stimulate cyclosporin A-sensitive transition in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). It acts as a stimulator of mitochondrial ion fluxes.

Phenylarsine oxide inhibits internalization of cell surface receptors; inhibits tyrosine phosphatases, with no effect on tyrosine kinase. Metabolic poison.

특징 및 장점

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H331,H410
• 예방조치 성명서: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable