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Merck
모든 사진(2)

주요 문서

MAK184

Sigma-Aldrich

Succinate Colorimetric Assay Kit

Sufficient for 100 Colorimetric tests

동의어(들):

Succinic Acid Assay Kit

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About This Item

EC Number:
UNSPSC 코드:
12161503
NACRES:
NA.84

응용 분야

cosmetics
food and beverages

검출 방법

colorimetric

관련 질환(들)

cardiovascular diseases; immunological diseases

저장 온도

−20°C

일반 설명

Succinate (succinic acid) is a citric acid cycle intermediate and functions in the transport of electrons to the mitochondrial electron transport chain. It also functions in innate immune signaling and induces IL-1β production during inflammation. Succinates have been often used for the treatment of hypertension. Succinate measurements can be useful for studying its metabolic, immunological, and therapeutic activities.

애플리케이션

Succinate Colorimetric Assay Kit has been used to measure the concentration of succinate.

적합성

Suitable for the detection of succinate in a variety of samples such as cell and tissue culture supernatants and in liquid samples such as wine.

원리

The Succinate Colorimetric Assay Kit is a highly sensitive assay for determining succinate levels (ranging from 2-10 nmole/well) in a variety of samples. Succinate concentration is determined by a coupled enzyme reaction, which results in a colorimetric (450 nm) product proportional to the succinate present.

키트 구성품 전용

제품 번호
설명

  • Succinate Assay Buffer

  • Succinate Converter

  • Succinate Enzyme Mix

  • Succinate Substrate Mix

  • Succinate Developer

  • Succinate Standard

픽토그램

Health hazardCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Electron Transport and Oxidative Phosphorylation
Lodish H, et al.
Molecular Cell Biology (2000)
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
Tretter L, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1857(8), 1086-1101 (2016)
VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.
Li J, et al.
Nature Communications, 8(1), 1322-1322 (2017)
Metoprolol succinate extended release/hydrochlorothiazide combination tablets.
Hainer JW and Jennifer S
Vascular Health, 3(3), 279-279 (2007)
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.
Shen J, et al.
JCI insight, 2(12) (2017)

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