L5647

Lidocaine hydrochloride monohydrate

≥99% (HPLC), solid, Na⁺ channel blocker

• 동의어(들): 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride monohydrate, Lignocaine hydrochloride monohydrate, Xylocaine hydrochloride monohydrate
• 실험식(Hill 표기법): C₁₄H₂₂N₂O · HCl · H₂O
• CAS Number: 6108-05-0
• Molecular Weight: 288.81
• EC Number: 200-803-8
• MDL number: MFCD00150329
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277718
• NACRES: NA.77

속성

• 제품명: Lidocaine hydrochloride monohydrate, solid
• 양식: solid
• 색상: white
• solubility: H₂O: soluble
• SMILES string: Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
• InChI key: YECIFGHRMFEPJK-UHFFFAOYSA-N
• 유전자 정보: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

설명

일반 설명

Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.

애플리케이션

Lidocaine hydrochloride monohydrate has been used:

• in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).
• to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.
• For inhibition of glial cells in brain tissue samples.

생화학적/생리학적 작용

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration

Na⁺ channel blocker; class IB antiarrhythmic.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves