L020000

TCA Deblock

• UNSPSC 코드: 41116105
• NACRES: NA.21

속성

• 유형: for DNA synthesis, for DNA synthesis; for DNA synthesis
• Quality Level: 200
• 저장 조건: dry at room temperature
• 농도: 28-32 g/L (TCA content, titration)
• 불순물: ≤200 ppm water content (Karl Fischer)
• 색상: clear; clear

설명

제조 메모

Trichloroacetic acid / Dichloromethane 3/100 (v/v)

기타 정보

Deblock solution containing trichloroacetic acid (TCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

안전성 정보

• 픽토그램: GHS08,GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H315,H318,H335,H336,H351,H411
• 예방조치 성명서: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Chronic 2 - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Central nervous system, Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point (°F): 212.0 °F - closed cup
• Flash Point (°C): 100 °C - closed cup