L040030

Cap A

configured for ABI

• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• 유형: for DNA synthesis
• 제품 라인: Proligo Reagents
• 양식: liquid
• 유통기한: 365 days
• 농도: 97.0-119.0 g/L (Acetic Anhydride content, titration)
• 색상: clear colorless, to brownish
• 호환성: configured for ABI
• 저장 온도: 2-8°C

설명

일반 설명

Cap A solution contains acetic anhydrideanhydride, lutidine and tetrahydrofuran (THF). It is used after the phosphoramidite reaction/coupling step. The solution is configured for ABI.

생화학적/생리학적 작용

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

제조 메모

Tetrahydrofurane / Lutidine / Acetic Anhydride 8/1/1 (v/v/v)

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302,H315,H318,H331,H335,H336,H351
• 예방조치 성명서: P210 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• 보충제 위험성: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 6.1 °F
• Flash Point (°C): -14.4 °C