G5044

GR 32191B

≥98% (HPLC), solid

• 동의어(들): (4Z)-7-[(1R,2R,3S,5S)-5-([1,1′-Biphenyl]-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl]-4-heptenoic acid hydrochloride
• 실험식(Hill 표기법): C₃₀H₄₀NO₄Cl
• CAS Number: 87248-13-3
• Molecular Weight: 514.10
• MDL number: MFCD04113055
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329799744
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: solid
• 색상: off-white
• mp: 127-128 °C
• solubility: H₂O: ~16 mg/mL
• 주관자: GlaxoSmithKline
• 배송 상태: wet ice
• 저장 온도: −20°C
• SMILES string: Cl.O[C@H]1C[C@H](OCc2ccc(cc2)-c3ccccc3)[C@H](CC\C=C/CCC(O)=O)[C@H]1N4CCCCC4
• InChI: 1S/C30H39NO4.ClH/c32-27-21-28(35-22-23-15-17-25(18-16-23)24-11-5-3-6-12-24)26(13-7-1-2-8-14-29(33)34)30(27)31-19-9-4-10-20-31;/h1-3,5-6,11-12,15-18,26-28,30,32H,4,7-10,13-14,19-22H2,(H,33,34);1H/b2-1-;/t26-,27-,28-,30+;/m0./s1
• InChI key: ZYOBZRTZRQKKNC-UGNABIHOSA-N

설명

생화학적/생리학적 작용

Selective TP prostanoid receptor antagonist. Inhibits U-46619-induced contraction of guinea pig trachea with IC₅₀=1.8 nM.

특징 및 장점

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

법적 정보

Manufactured and sold under agreement from Glaxo­Smith­Kline

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)