E1905

(+)-Etomoxir sodium salt hydrate

≥98% (HPLC), powder, CPT-1 inhibitor

• 동의어(들): R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate
• 실험식(Hill 표기법): C₁₅H₁₈ClO₄ · Na · H₂O
• CAS Number: 828934-41-4
• Molecular Weight: 338.76
• MDL number: MFCD11044452
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24724474
• NACRES: NA.77

속성

• 제품명: (+)-Etomoxir sodium salt hydrate, ≥98% (HPLC), powder
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white
• solubility: H₂O: freely soluble
• 저장 온도: 2-8°C
• SMILES string: O.[Na+].[O-]C(=O)[C@@]2(CCCCCCOc1ccc(Cl)cc1)CO2
• InChI: 1S/C15H19ClO4.Na.H2O/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;;/h5-8H,1-4,9-11H2,(H,17,18);;1H2/q;+1;/p-1/t15-;;/m1../s1
• InChI key: WENJLJJSJDAJDN-QCUBGVIVSA-M

설명

일반 설명

(+)-Etomoxir sodium salt hydrate belongs to oxirane carboxylic acid group of compounds and mediates metabolic channeling of fatty acid precursors. It favors oxidative stress in T cells and prevents T cell differentiation. It inhibits fatty acid oxidation and promotes hunger and food intake. Etomoxir impairs myeloid-derived suppressor cells mediated tumor and could have potential therapeutic potential.

애플리케이션

(+)-Etomoxir sodium salt hydrate has been used as an inhibitor of carnitine palmitoyltransferase 1 (CPT-1) in breast tumor cell lines and mice tumor. It has also been used as an inhibitor of fatty acid oxidation in human primary prostate epithelial cells and lymphocytes.

생화학적/생리학적 작용

Irreversible O-carnitine palmitoyltransferase-1 (CPT-1) inhibitor; PPARα activator

포장

Store tightly sealed, protected from exposure to light

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves