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Merck
모든 사진(2)

Key Documents

추가 자료

B019

Sigma-Aldrich

Phenoxybenzamine hydrochloride

≥97%, powder

동의어(들):

N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C18H22ClNO · HCl
CAS Number:
63-92-3
Molecular Weight:
340.29
EC Number:
200-569-7
MDL number:
MFCD00055152
UNSPSC 코드:
12352116
PubChem Substance ID:
24277760
NACRES:
NA.77

Quality Level

100

분석

≥97%

형태

powder

색상

white

solubility

H2O: slightly soluble
alcohol: soluble
propylene glycol: soluble

주관자

Wellspring

저장 온도

2-8°C

SMILES string

Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2

InChI

1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H

InChI key

VBCPVIWPDJVHAN-UHFFFAOYSA-N

유전자 정보

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Calmodulin antagonist; α-adrenoceptor antagonist.

특징 및 장점

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Wellspring. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Warning

유해 및 위험 성명서

H302,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yu Zhu et al.
Endocrine, 38(2), 254-259 (2010-11-04)
The objective of this article is to evaluate the efficacy of Doxazosin Mesylate Controlled Release Tablets for preoperative treatment of patients with pheochromocytoma. Between 2003 and 2008, 67 patients with confirmed diagnoses of pheochromocytoma were enrolled in this study. According
João Walter S Silveira et al.
Molecular pain, 6, 17-17 (2010-03-25)
Descending pronociceptive pathways may be implicated in states of persistent pain. Paw skin incision is a well-established postoperative pain model that causes behavioral nociceptive responses and enhanced excitability of spinal dorsal horn neurons. The number of spinal c-Fos positive neurons
Brian T Welch et al.
Radiology, 258(1), 301-307 (2010-10-26)
To assess safety, technical success, complications, and hemodynamic changes associated with the adrenal cryoablation procedure. This retrospective review was approved by the institutional review board, with waiver of informed consent, and was compliant with the Health Insurance Portability and Accountability
Is dexmedetomidine the agent of choice in the resection of pheochromocytoma?
Harsha V Polavarapu et al.
The American surgeon, 78(3), E127-E128 (2012-04-25)
Hasan K Siddiqi et al.
Surgery, 152(6), 1027-1036 (2012-11-20)
Calcium channel blockade with nicardipine (NC) is an alternative to phenoxybenzamine (PB) preparation for resection of a pheochromocytoma. Intraoperative magnesium sulfate infusion (+MgSO(4)) is often used for its cardiovascular stabilizing properties. We hypothesized that preparation with NC would be similar
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