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Merck
모든 사진(1)

문서

43799

Sigma-Aldrich

N-Palmitoyl-D-sphingosine

≥98.0% (TLC)

동의어(들):

Cer(d18:1/16:0), (2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-1,3-diol, N-Hexadecanoyl-D-sphingosine, N-Palmitoyl-D-erythro-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexadecanamide, C16 Ceramide (d18:1/16:0), C16-Ceramide

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C34H67NO3
CAS Number:
24696-26-2
Molecular Weight:
537.90
MDL number:
MFCD00871748
UNSPSC 코드:
12352211
PubChem Substance ID:
329756403
NACRES:
NA.85

분석

≥98.0% (TLC)

형태

powder or solid

구성

carbon content, 75.92%
hydrogen content, 12.55%
nitrogen content, 2.60%

작용기

amide

지질 유형

sphingolipids

배송 상태

wet ice

저장 온도

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1

InChI key

YDNKGFDKKRUKPY-TURZORIXSA-N

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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16:0 SM (d18:1/16:0) Avanti Research™ - A Croda Brand, powder

Avanti

860584P

16:0 SM (d18:1/16:0)

Sphingomyelin from chicken egg yolk, ≥95%

Sigma-Aldrich

S0756

Sphingomyelin

1,3-Dipalmitoyl-2-oleoylglycerol ≥99%

Sigma-Aldrich

D2157

1,3-Dipalmitoyl-2-oleoylglycerol

Gloria I Perez et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(7), 860-862 (2005-02-25)
An age-dependent acceleration of apoptosis occurs in female germ cells (oocytes), and this requires communication between the oocyte and its surrounding somatic (cumulus) cells. Here we show in aged mice that ceramide is translocated from cumulus cells into the adjacent
S White-Gilbertson et al.
Oncogene, 28(8), 1132-1141 (2009-01-13)
We have previously shown that the death receptor ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces an increase of intracellular C(16)-ceramide in sensitive SW480 but not in resistant SW620 cells. Resistance in SW620 cells was overcome by exogenous ceramide, leading
Claudia Almeida et al.
PloS one, 13(8), e0201373-e0201373 (2018-08-11)
Biological membranes contain a large variety of lipids species compartmentalized in different domains heterogeneous in size, composition and dynamics. Cholesterol induces membrane ordered domains thanks to its affinity for saturated lipids. Membrane domains had been studied with fluorescent probes either
Daniel Dindo et al.
Molecular cancer therapeutics, 5(6), 1520-1529 (2006-07-05)
Ceramides are sphingolipid second messengers that are involved in the mediation of cell death. There is accumulating evidence that mitochondria play a central role in ceramide-derived toxicity. We designed a novel cationic long-chain ceramide [omega-pyridinium bromide D-erythro-C16-ceramide (LCL-30)] targeting negatively
Jérôme Becam et al.
Scientific reports, 7(1), 17627-17627 (2017-12-17)
Certain fatty acids and sphingoid bases found at mucosal surfaces are known to have antibacterial activity and are thought to play a more direct role in innate immunity against bacterial infections. Herein, we analysed the antibacterial activity of sphingolipids, including
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