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Merck
  • Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria.

Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria.

Scientific reports (2017-12-17)
Jérôme Becam, Tim Walter, Anne Burgert, Jan Schlegel, Markus Sauer, Jürgen Seibel, Alexandra Schubert-Unkmeir
초록

Certain fatty acids and sphingoid bases found at mucosal surfaces are known to have antibacterial activity and are thought to play a more direct role in innate immunity against bacterial infections. Herein, we analysed the antibacterial activity of sphingolipids, including the sphingoid base sphingosine as well as short-chain C

MATERIALS
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Sigma-Aldrich
Ribonuclease A from bovine pancreas, (Solution of 50% glycerol, 10mM Tris-HCL pH 8.0)
Sigma-Aldrich
N-Palmitoyl-D-sphingosine, ≥98.0% (TLC)