모든 사진(1)
About This Item
실험식(Hill 표기법):
C5H11N
CAS Number:
Molecular Weight:
85.15
Beilstein:
102438
EC Number:
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.21
Grade:
biotech. grade
분석:
≥99.5%
기술:
DNA sequencing: suitable
bp:
106 °C (lit.)
106 °C
106 °C
vapor pressure:
23 mmHg ( 20 °C)
추천 제품
Grade
biotech. grade
Quality Level
vapor density
3 (vs air)
vapor pressure
23 mmHg ( 20 °C)
분석
≥99.5%
양식
liquid
기술
DNA sequencing: suitable
불순물
<0.3% water
refractive index
n20/D 1.452 (lit.)
bp
106 °C (lit.)
106 °C
mp
−13 °C (lit.)
solubility
organic solvents: soluble(lit.)
water: miscible(lit.)
density
0.862 g/mL at 20 °C (lit.)
λ
1 cm path, H2O reference
UV 흡수
λ: 290 Amax: <1.000
λ: 370 Amax: <0.050
SMILES string
C1CCNCC1
InChI
1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2
InChI key
NQRYJNQNLNOLGT-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Piperidine, a heterocyclic cyclohexane is a volatile secondary amine. Maxam-Gilbert chemical method, a DNA sequencing technology employs piperidine to rupture DNA strands at damaged base site. Its crystal structure analyzed at 150K shows hydrogen bonding between NH groups. Piperidine ring forms a part of many naturally occuring alkaloids. It is prepared on an industrial scale by the hydrogenation of pyridine in the presence of nickel catalyst. The 1H NMR spectrum of piperidine has been recorded.
애플리케이션
Fits Applied Biosystems 431 and 433A peptide synthesizers.
Piperidine has been used in combination with DMF (dimethylformamide) for the removal of Fmoc (fluorenylmethyloxycarbonyl) group from the N-terminal amino group during peptide synthesis.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point (°F)
60.8 °F - closed cup
Flash Point (°C)
16 °C - closed cup
이미 열람한 고객
W B Mattes et al.
Biochimica et biophysica acta, 868(1), 71-76 (1986-10-16)
The volatile, secondary amine piperidine is used in the Maxam-Gilbert chemical method of DNA sequencing to create strand breaks in DNA at sites of damaged bases. As such it is often used in generalized studies of DNA damage to identify
Peptide Synthesis.
Miao Z and Cheng Z
Bio-protocol, 2(14) (2012)
Andrew Parkin et al.
Acta crystallographica. Section B, Structural science, 60(Pt 2), 219-227 (2004-03-16)
The crystal structures of piperazine, piperidine and morpholine have been determined at 150 K. All three structures are characterized by the formation of NH...N hydrogen-bonded chains. In piperazine these are linked to form sheets, but the chains are shifted so
Xuwang Chen et al.
Bioorganic & medicinal chemistry, 20(12), 3856-3864 (2012-05-18)
A novel series of piperidine-linked amino-triazine derivatives were designed, synthesized and evaluated for in vitro anti-HIV activity as non-nucleoside reverse transcriptase inhibitors on the basis of our previous work. Screening results indicated that most compounds showed excellent activity against wild-type
Marek Łuczkowski et al.
Inorganic chemistry, 47(23), 10875-10888 (2008-10-31)
A de novo protein design strategy provides a powerful tool to elucidate how heavy metals interact with proteins.Cysteine derivatives of the TRI peptide family (Ac-G(LKALEEK)4G-NH2) have been shown to bind heavy metals in an unusual trigonal geometry. Our present objective
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