PHR1304
Butylated hydroxyanisole
Pharmaceutical Secondary Standard; Certified Reference Material
동의어(들):
2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA
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모든 사진(1)
About This Item
Linear Formula:
(CH3)3CC6H3(OCH3)OH
CAS Number:
Molecular Weight:
180.24
EC Number:
MDL number:
UNSPSC 코드:
41116107
NACRES:
NA.24
추천 제품
Grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to Ph. Eur. B1212000
traceable to USP 1083008
vapor density
6.2 (vs air)
API family
butylhydroxyanisole
CofA
current certificate can be downloaded
autoignition temp.
599 °F
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
58-60 °C (lit.)
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-30°C
SMILES string
O(C)c1cc(c(cc1)O)C(C)(C)C
InChI
1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
InChI key
MRBKEAMVRSLQPH-UHFFFAOYSA-N
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일반 설명
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
애플리케이션
Butylated hydroxyanisole (BHA) may be used as a reference standard for the determination of the analyte in pharmaceutical creams by spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
분석 메모
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
기타 정보
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
각주
To see an example of a Certificate of Analysis for this material enter LRAB3751 in the slot below. This is an example certificate only and may not be the lot that you receive.
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Aquatic Chronic 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
241.9 °F - Pensky-Martens closed cup
Flash Point (°C)
116.6 °C - Pensky-Martens closed cup
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Determination of miconazole in pharmaceutical creams using internal standard and second derivative spectrophotometry.
Wrobel K, et al.
Journal of Pharmaceutical and Biomedical Analysis, 20(1-2), 99-105 (1999)
[Modification of the processes of chemical mutagenesis and carcinogenesis by synthetic phenol antioxidants such as butylated hydroxyanisole].
K Demkowicz-Dobrzański et al.
Postepy biochemii, 38(1), 37-42 (1992-01-01)
H Verhagen et al.
Chemico-biological interactions, 80(2), 109-134 (1991-01-01)
Butylated hydroxyanisole (BHA) is a synthetic food antioxidant used to prevent oils, fats and shortenings from oxidative deterioration and rancidity. This review depicts the current knowledge on BHA. The physical and chemical characteristics of BHA are summarized and its function
J Whysner et al.
Pharmacology & therapeutics, 71(1-2), 137-151 (1996-01-01)
Butylated hydroxyanisole (BHA), at high doses, has been found to induce forestomach squamous cell carcinomas in rodents, but not glandular cell or other types of neoplasms. BHA is not DNA-reactive, and the epigenetic mechanism of tumor formation involves cytotoxicity and
G M Williams
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(10-11), 1163-1166 (1986-10-01)
Studies on the potential genotoxicity and epigenetic effects of BHA are reviewed. BHA was not DNA-reactive, but studies showed that it did have an effect on membrane systems, blocking exchange between hepatocytes and epithelial cells. The available data strongly suggest
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