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Merck
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Key Documents

I2399

Sigma-Aldrich

Imidazole

ACS reagent, ≥99% (titration)

동의어(들):

1,3-Diaza-2,4-cyclopentadiene, Glyoxaline

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About This Item

실험식(Hill 표기법):
C3H4N2
CAS Number:
Molecular Weight:
68.08
Beilstein:
103853
EC Number:
MDL number:
UNSPSC 코드:
12352005
eCl@ss:
39161001
PubChem Substance ID:
NACRES:
NA.21

Grade

ACS reagent

Quality Level

vapor pressure

<1 mmHg ( 20 °C)

분석

≥99% (titration)

불순물

≤0.2% water

무기 잔류물

≤0.1%

pH

9.5-11.0 (25 °C, 5% in H2O)

pKa(25 °C)

6.95

bp

256 °C (lit.)

mp

88-91 °C (lit.)

양이온 미량물

Fe: ≤0.001%

SMILES string

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChI key

RAXXELZNTBOGNW-UHFFFAOYSA-N

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일반 설명

Imidazole is a five-membered heterocycle that is found in many naturally occurring compounds. It exhibits both acidic and basic properties. It is reported to be an inhibitor of thromboxane formation. Its vertical spectrum and the radiationless decay have been recorded and analyzed.

애플리케이션

Excellent for buffers in the range of pH 6.2-7.8

법적 정보

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

픽토그램

Health hazardCorrosionExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

293.0 °F - closed cup

Flash Point (°C)

145 °C - closed cup

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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문서 라이브러리 방문

이미 열람한 고객

UV excitation and radiationless deactivation of imidazole.
Barbatti M, et al.
J. Chem. Phys., 130(3), 034305-034305 (2009)
Zhong Jin
Natural product reports, 28(6), 1143-1191 (2011-04-08)
A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazole, oxazole, thiazole, and their saturated congeners, are abundant in nature. These naturally occurring metabolites often exhibit extensive and pharmacologically important biological activities. The latest progress
S Moncada et al.
Prostaglandins, 13(4), 611-618 (1977-04-01)
Imidazole inhibits the enzymic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes (IC50: 22 MICRONG/ML; DETERMINED BY BIOASSAY). The inhibitor is selective, for prostaglandin cyclo-oxygenase is only affected at high doses. Radiochemical data confirms that
Peter Canning et al.
Journal of molecular biology, 426(13), 2457-2470 (2014-04-29)
The discoidin domain receptors (DDRs), DDR1 and DDR2, form a unique subfamily of receptor tyrosine kinases that are activated by the binding of triple-helical collagen. Excessive signaling by DDR1 and DDR2 has been linked to the progression of various human
Pam M Van Ry et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 23(8), 1285-1297 (2015-06-09)
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