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Merck
모든 사진(2)

주요 문서

D4065

Supelco

Dirithromycin

analytical standard, for drug analysis

동의어(들):

[9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxy)ethylidene]oxy]erthromycin; LY-237216

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About This Item

실험식(Hill 표기법):
C42H78N2O14
CAS Number:
Molecular Weight:
835.07
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:

Grade

analytical standard, for drug analysis

Quality Level

분석

≥95% (TLC)

양식

solid

분자량

apparent mol wt 835.1

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

형식

neat

SMILES string

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C4N[C@@H](COCCOC)OC([C@H]4C)[C@]1(C)O

InChI

1S/C42H78N2O14/c1-15-29-42(10,49)37-24(4)32(43-30(56-37)21-52-17-16-50-13)22(2)19-40(8,48)36(58-39-33(45)28(44(11)12)18-23(3)53-39)25(5)34(26(6)38(47)55-29)57-31-20-41(9,51-14)35(46)27(7)54-31/h22-37,39,43,45-46,48-49H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,30-,31+,32+,33-,34+,35+,36-,37-,39+,40-,41+,42-/m1/s1

InChI key

WLOHNSSYAXHWNR-KZYCBHIHSA-N

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일반 설명

Chemical structure: macrolide

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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문서 라이브러리 방문

From the Centers for Disease Control and Prevention. Sudden death in a traveler following halofantrine administration--Togo, 2000.
JAMA, 285(14), 1836-1836 (2001-04-28)
I Moutard et al.
Therapie, 54(5), 607-612 (2000-02-10)
Polymorphonuclear neutrophils are the predominant cells in acute inflammatory lesions and their functions and recruitment are regulated by cytokines, including IL1, TNF and IL8. Antibiotic modulation of inflammatory effects has stimulated investigations of antibiotics for their potential activity as immunomodulators
J Diana et al.
Journal of chromatography. A, 1125(1), 52-66 (2006-06-20)
With a recently developed liquid chromatographic (LC) method, using a phosphate buffer, several unknown impurities present in dirithromycin samples were separated. In this paper, a reversed-phase liquid chromatography-tandem mass spectrometry method is described for the investigation of dirithromycin and related
Yun-Qing Liu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 864(1-2), 1-8 (2008-02-26)
A sensitive, rapid liquid chromatographic-electrospray ionization mass spectrometric method for determination of erythromycylamine in human plasma was developed and validated. Erythromycylamine in plasma (0.2 mL) was extracted with ethyl acetate, the organic phase was transferred to another clear 1.5 mL
Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analyisis and studies on acellular and cell culture models. .
Montenez, J. P., et al.
Toxicology and Applied Pharmacology, 15, 129-129 (1999)

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