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Merck
모든 사진(1)

주요 문서

B5774

Supelco

Benzbromarone

analytical standard

동의어(들):

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran

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About This Item

실험식(Hill 표기법):
C17H12Br2O3
CAS Number:
Molecular Weight:
424.08
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

분석

~95%

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

형식

neat

저장 온도

2-8°C

SMILES string

CCc1oc2ccccc2c1C(=O)c3cc(Br)c(O)c(Br)c3

InChI

1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3

InChI key

WHQCHUCQKNIQEC-UHFFFAOYSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Tip W Loo et al.
Biochemistry, 50(21), 4393-4395 (2011-04-28)
Deletion of Phe508 from the first nucleotide-binding domain of the CFTR chloride channel causes cystic fibrosis because it inhibits protein folding. Indirect approaches such as incubation at low temperatures can partially rescue ΔF508 CFTR, but the protein is unstable at
Atsushi Iwamura et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(5), 838-846 (2011-02-16)
Drug-induced hepatotoxicity is a major problem in drug development, and reactive metabolites generated by cytochrome P450s are suggested to be one of the causes. CYP2C9 is one of the major enzymes in hepatic drug metabolism. In the present study, we
Fernanda Cristina Mazali et al.
Nephron. Experimental nephrology, 120(1), e12-e19 (2011-12-01)
Hyperuricemia frequently complicates cyclosporine (CsA) therapy. Previous studies have shown that hyperuricemia exacerbates interstitial and vascular lesions in the cyclosporine model. We tested the hypothesis that normalization of uric acid could prevent the development of cyclosporine toxicity. CsA nephropathy was
Tip W Loo et al.
Biochemical pharmacology, 83(3), 345-354 (2011-12-06)
The most common cause of cystic fibrosis is deletion of Phe508 in the first nucleotide-binding domain (NBD) of the CFTR chloride channel, which inhibits protein folding. ΔF508 CFTR can be rescued by indirect approaches such as low temperature but the
Kaoru Kobayashi et al.
Biopharmaceutics & drug disposition, 33(8), 466-473 (2012-08-31)
Benzbromarone (BBR) is metabolized to 1'-hydroxy BBR and 6-hydroxy BBR in the liver. 6-Hydroxy BBR is further metabolized to 5,6-dihydroxy BBR. The aim of this study was to identify the CYP isozymes involved in the metabolism of BBR to 1'-hydroxy

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